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Sperm thermotaxis : ウィキペディア英語版 | Sperm thermotaxis Sperm thermotaxis is a form of sperm guidance, in which sperm cells (spermatozoa) actively change their swimming direction according to a temperature gradient, swimming up the gradient. Thus far this process has been discovered in mammals only. == Background ==
The discovery of mammalian sperm chemotaxis and the realization that it can guide spermatozoa for short distances only〔Bahat, A., Tur-Kaspa, I., Gakamsky, A., Giojalas, L. C., Breitbart, H. and Eisenbach, M. (2003) ''Thermotaxis of mammalian sperm cells: A potential navigation mechanism in the female genital tract.'' Nature Med. 9, 149-150.〕 (estimated at the order of millimeters),〔Pérez-Cerezales, S., Boryshpolets, S. and Eisenbach, M. (2015) ''Behavioral mechanisms of mammalian sperm guidance''. Asian J. Androl. 17, 628-632.〕 triggered a search for potential long-range guidance mechanisms. The findings that, at least in rabbits〔David A, Vilensky A, Nathan H. (1972) ''Temperature changes in the different parts of the rabbit's oviduct''. Int. J. Gynaec. Obstet. 10, 52-56.〕 and pigs,〔Hunter RH, Nichol R. (1986) ''A preovulatory temperature gradient between the isthmus and ampulla of pig oviducts during the phase of sperm storage''. J. Reprod. Fertil. 77, 599-606.〕 a temperature difference exists within the oviduct, and that this temperature difference is established at ovulation in rabbits due to a temperature drop in the oviduct near the junction with the uterus, creating a temperature gradient between the sperm storage site and the fertilization site in the oviduct,〔Bahat, A., Eisenbach, M. and Tur-Kaspa, I. (2005) ''Periovulatory increase in temperature difference within the rabbit oviduct''. Hum. Reprod. 20, 2118-2121.〕 led to investigation whether mammalian spermatozoa can respond to a temperature gradient by thermotaxis.
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